Production of anti-rat islet cell surface antibody in guinea pigs.

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Production of anti-rat islet cell surface antibody in guinea pigs.

Anti-rat islet serum was prepared in guinea pigs by multiple subcutaneous inoculations of rat islets homogenates emulsified in complete Freund's adjuvant (CFA). The anti-rat islet serum was cytotoxic against rat spleen cells in the presence of complement and the nonspecific antibodies were observed with homogenates of rat livers and spleens. After absorption, the serum lost the cytotoxicity aga...

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By careful aseptic operation it was found possible to remove approximately three-quarters to seven-eighths of the adrenal tissue of guinea pigs without causing symptoms of adrenal insufficiency. Guinea pigs were immunized to Bacillus typhosus or to hen corpuscles at varying intervals before or after the operation, and the curves of antibody formation traced for 2 to 3 months after immunization....

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Antitussive Effect of Plantago lanceolata in Guinea Pigs

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ژورنال

عنوان ژورنال: Endocrinologia Japonica

سال: 1982

ISSN: 0013-7219,2185-6370

DOI: 10.1507/endocrj1954.29.395